More often than you would think the biggest problem with a CiviCRM install are due to the first choices made by the installer. Checking that box seemed like a good idea at the time, but it is creating nothing but havoc right now.
Tommy Bobo, who handles the majority of Civi911 calls and has seen your database nightmares, will take you through the list of problems that just keep coming up, and which choices are just time bombs waiting to explode.
Should you turn on Logging, Watchdog Logging, or both? Is CiviGrant for me? Of course you should accept Philippine Pesos? Is 123456789 a valid site key? Should your board members have their own contact subtype?